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Jul
12

Cocaine Drug Information

by admin

Classification

Cocaine (benzoylmethylecgonine) is a central nervous system stimulant derived from the leaves of the coca plant. Cocaine has two major pharmacological actions; one is a local anesthetic, and the other is an indirect acting sympathomimetic having many of the properties of an amphetamine. The drug is either in the salt/powder form (cocaine HCL) which can be administered by snorting or intravenous injection or in the free base “crack” form which is smoked.

Metabolism

After smoking, cocaine is rapidly absorbed with peak plasma concentrations occurring at about 5 minutes, versus 30-40 minutes following intranasal ingestion. Cocaine is extensively metabolized by the liver and blood enzymes with approximately one percent of the dose excreted in the urine unchanged. The major metabolite found in the urine is benzoylecgonine (25-40% of the dose), followed by ecgonine methyl ester (18-22%). Depending upon the dosage ingested, frequency of use, and metabolic variation, benzoylecgonine can remain detectable in the urine for as long as 48-96 hours post ingestion.

Abuse

Cocaine produces a short-lived, intense high which is extremely addictive. The signs and symptoms associated with the abuse of cocaine depend upon the amount used and the duration of use. With infrequent or low dose use a person may experience euphoria, lowered anxiety, talkativeness, decreased appetite, increased sexual arousal, increased alertness, and decreased fatigue. Physiologically there can be increased heart rate and blood pressure.

With increased dose or prolonged abuse (either binge or chronic) an individual may experience a set of secondary effects that can include increased anxiety, irritability, aggressiveness, paranoia and hypersexuality. Physiological effects can include dilated pupils, dry mouth, hippus, increased body temperature and tachycardia. In overdose situations, a person my experience hallucinations, coma or death. Crash symptoms typically follow binge abuse of cocaine. This phase is marked by extreme fatigue, depression, mental exhaustion and prolonged periods of sleep.

Laboratory drug testing: Methods of Analysis

The immunoassay methods (EIA, RIA, FPIA) are widely used screening methods designed to specifically detect benzoylecgonine and to lesser extents, cocaine and ecgonine methyl ester (secondary cocaine metabolite). Commonly used confirmation methods include thin layer chromatography (TLC), high pressure liquid chromatography (HPLC), gas chromatography (GC), and gas chromatography/mass spectrometry (GC/MS). GC/MS methods offer excellent sensitivity and specificity and are the methods of choice for the confirmation of the immunoassay positive screens.

 

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Jun
29

Controlled Substances-Mere Possession can be Trafficking

by admin

In the State of Florida, the mere possession of certain controlled substances , even in very small amounts can carry trafficking minimum mandatory prison sentences. This article addresses the penalties associated with the simple possession a class of narcotic drugs, hydrocodone. These includes well known, generic and inexpensive mid to mild pain killers Lortabs, Percocet, Darvocet. The possession of these drugs in Florida state court is far more serious that in any federal court through out the entire county.

The reasons why possession of hydrocodone, a.k.a. Lortab, Percocet, Darvocet, etc., is because several years ago the Florida Legislature amended Chapter 893, the drug statute in Florida, and enhanced the possession of hydrocodone from a schedule III drug to a Schedule II drug. What happens in the cases of Class II drugs is that not only the inert “illegal” ingredient of the drug will be factored into the equation of the weight of the drug but the “filler” or other compounds or ingredients mixed in with the inert or narcotic ingredient will be added into the total weight of the pill. So, for example, in Lortabs, or hydrocodone, which consists primarily of acetaminophen, the same ingredient that makes up Tylenol, an over the counter pain medication, will be used in the total weight calculation.

What this means is that possession of more than six tablets of Lortab is a three year minimum prison sentence, possession of thirty of these pills is a fifteen-year minimum mandatory and possession of a 100 of Lortabs without prescription is a twenty-five year minimum mandatory! These mandatories do not apply to only those who sell, deliver or give Lortabs or hydrocone to other people. The mere possession of these quantities is trafficking!! So, for example, the friend who gives a buddy six Lortab 10s not only is “trafficking” because the friend had an acute injury and is in pain, will also be guilty of a three year minimum mandatory by merely possessing the drug!

The legislature has made mere possession of one of the most widely used mild-mid level pain killers, hydrocodone or Lortabs, a mandatory prison sentence if you have only six tablets!

The policy behind the legislature moving hydrocodone to a Class II drug from a Class III drug is Class II drugs are more addictive in nature that Class III. For example, cocaine is Class II drug. Diet pills are Class III or Class IV drugs and the “mixture of other substances” and not added to the controlled substance and are not counted in the total weight calculation.

Travesties are occurring around Florida when first time offenders are arrested with a small number of these drugs and receive long minimum mandatory prison sentences. The only way the law is going to change is for the legislature to reclassify hydrocodone to a Class III drug. But being realistic, how many politicians, politics being what they are, are going to want to sponsor a bill making possession of a narcotic drug less severe?  Some will one day, when one of their constituents, or one of their loved ones or family members gets ensnared by this terrible law.

Cocaine, methamphetamine, heroin and other Class II and Class I narcotics all carry various miniminum mandatory prison sentences if someone merely possesses a certain amount of the drug, even if it is for personal use. For instance, some cocaine users, who have the funds, prefer to purchase one ounce (28.4 grams) of cocaine at one time from their drug dealer so they don’t have to take the risks of making multiple trips to the dealers house, carrying the illegal substance in their car, etc.

The mere possession of 28 grams or more of cocaine, regardless of the purity of the cocaine, in Florida turns the offense into a three year minimum mandatory prison sentence. What this means is the judge, if a person is convicted, must impose three years of state prison time regardless whether it is the offender’s first offense and even if the criminal code score sheet (sentencing guidelines used by the Courts) call for less than three years of incarceration for this quantity of cocaine. Many judges, both federal and state, are outspoken about the harshness of these politically charged laws.

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